Israeli technology helps diabetics control sugar levels and eat whatever they want

“Generic diets for patients with diabetes often don’t work,” says Amit Golan, vice president of business development and strategic partnerships for DayTwo. “If you tell someone to avoid carbs, most people won’t be able to stick with it in the long run. But even for something as unhealthy as ice cream, we can find ways to mitigate the damage so people can eat. occasionally. Using data to teach a person to combine foods based on their microbiome profile is more effective than generic diets and has higher levels of success. “

The medical world’s understanding of diabetes treatment has changed significantly in the past six years, Golan said in an interview for World Diabetes Day, an annual event created in 1991 to help raise awareness of the growing threat to diabetes. disease health.

The DayTwo system analyzes a person’s gut microbiome and uses artificial intelligence to predict their blood sugar response to food for a sustainable approach to managing type 2 diabetes and prediabetes.

“In 2015, Dr. Eran Segal of the Weitzman Institute published research from the largest study of its kind ever conducted at the time showing that people reacted much better to personalized diets,” Golan said. “He showed that if he had enough data, he could create an algorithm that could show how people will react to certain foods better than any system out there, with significant clinical impact. That created quite a stir, and we started getting calls from almost every health organizations. There had been some discussion about customization beforehand, but nobody knew how to do it and measure it. “

DayTwo’s solution begins when the customer mails a stool sample to the company’s lab near the Weitzman Institute in Rehovot. “We have no other way to analyze the microbes that you have,” Golan said. “So we send him the kit and he gives us the sample, which we use to run a sequencing analysis of his DNA for the bacteria. We also ask him for the results of some blood tests and ask him to complete a questionnaire about his lifestyle. put the data into our proprietary algorithm and it helps us predict, before you eat, how your particular body will react to specific food combinations. “

Sugar (credit: INGIMAGE)

Combining carbohydrates with other foods can mitigate some of the damage, but you need to know the correct foods to use, Golan said. “If you and I are having dinner together on Shabbat, my blood sugar level may rise from eating challah bread with tehina, while yours stays the same, because our bodies react differently. Some of this is about using the The right fats, like avocado, walnuts, olive oil, and the like. It means learning about the right kinds of combinations that work for your body. “

Ahead of World Diabetes Day on November 14, DayTwo published a new study showing that a personalized diet controls blood sugar levels significantly better than the Mediterranean diet, a favorite plan of diabetes patients for its focus on vegetables, whole grains and healthy fats. The average daily time that participants were above the normal range for blood sugar levels (above 140 mg) decreased by approximately 29% on the Mediterranean diet and by approximately 65% ​​on the DayTwo diet, according to the report. . More significantly, the people who used the personalized plan maintained lower blood sugar levels over a 12-month period, because the plan was less invasive in their lives.

‘Unlike most diets that prevent people from consuming a lot of food, our unique algorithm learns the user’s profile and allows people to make slight menu changes based on what they like, while still seeing a big impact on your sugar levels and maintaining your personal level. health principles over time, “said Michal Tzalach David, DayTwo’s lead dietitian.

DayTwo also offers a weight loss program that helps people maintain weight by learning to identify which foods are most troublesome for their bodies. Many of the people who follow the diabetes program also report that weight loss is a positive side effect.

“When you control your blood sugar, you are less hungry,” Golan said. Obesity, obviously, is not just about sugar, there are many factors such as stress, lifestyle, exercise, etc. But when we help people control their blood sugar levels and provide personal advice from professionals , excellent results are obtained “.

In the United States, DayTwo works with many of the largest health insurance providers and is available in many corporate health plans. In Israel, the company has agreements with the Clalit and Maccabi health funds, or it can be purchased privately through the company’s website,

Diabetes is growing rapidly around the world. In 2019, it was the direct cause of 1.5 million deaths, and the prevalence increased most rapidly in low- and middle-income countries. In Israel, diabetes is one of the leading causes of death, affecting 6.4% of adults over 18 years of age.

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