Vaccinated? Four factors could increase your risk of COVID infection

About two weeks after being vaccinated, your anti-corona antibody level is at its peak and you are considered to be fully vaccinated.

But, as some people discovered in the fourth wave of the pandemic, even two full doses of the vaccine do not guarantee 100% protection against infection. A progressive infection looks a lot like a normal corona infection, but there are important differences.

A study of corona symptoms shows that the five most common symptoms among coronavirus-infected vaccinated people are: headache, runny nose, sneezing, sore throat, and impaired sense of smell.

This sounds similar to the usual and familiar symptoms experienced by the unvaccinated.

But without the vaccine there are two other symptoms from which the vaccinated are saved: fever and persistent cough.

A study that compared symptoms between vaccinated and unvaccinated people found that a vaccinated person infected with corona had a 58% lower chance of developing a fever. Most of the people who got vaccinated and later infected said they felt more like they had a mild cold.

Another difference is the risk of being hospitalized.

Those vaccinated are much less likely to be hospitalized due to their symptoms and are less likely to suffer from long-term symptoms, often referred to as prolonged COVID.

What increases the risk of infection in vaccinated people?

A study in the United Kingdom found that the infection rate of those vaccinated is 0.2%, which means that one in every 500 people is infected despite being vaccinated.

However, the possibility of becoming infected despite the vaccine is not the same for everyone and there are four factors that increase the risk.(Credit: Flash90)


1 – Type of vaccine

Clinical studies conducted before the approval of the various vaccines, as well as data collected after the start of the vaccination campaign from the world population, gave each of the approved vaccines a score in terms of the relative reduction of infection .

For Pfizer, more common among Israelis, the vaccine is 95% effective in reducing infection. Moderna’s vaccine is very close, 94% efficient.

Other vaccines that have been approved and administered globally have reported less effective data: the Johnson & Johnson vaccine was 66% and the Astra-Zenica vaccine was 70%. So someone who has been vaccinated with one of the latter two has slightly less effective protection than someone vaccinated with Pfizer or Moderna.(Credit: Flash90)(Credit: Flash90)


2 – Time elapsed since the last dose was received

The time that elapses since the vaccine is administered turns out to be one of the most important factors in the level of antibodies and, therefore, also in the quality of immunization. That is why Israel decided to vaccinate the population with a third booster dose and it seems that the rest of the world will do the same.
Recent studies indicate that immune resistance as a result of Pfizer vaccines subsides during the first four to six months after the second vaccine.

(Credit: Flash90)(Credit: Flash90)

3 – Variants

The virus we are faced with today is not exactly the same one that broke into our lives almost two years ago. Rather, there are new versions and sometimes slightly improved ones.

Certain mutations that the virus underwent during its travels around the world brought us a variety of variants, now named after Latin letters of the alphabet. The Delta variant and its descendants have become the most dominant strain of the virus in most of the world.

The efficacy percentages of the vaccines were calculated in the experimental stage in relation to the original version of the virus. However, by the time they were approved and administered, the vaccines were asked to fend off slightly different versions of the virus.
Thus, the efficacy percentages of the Pfizer vaccine, which stood at 95% against the original virus, decreased slightly to 93% against the Alpha variant and 88% against Delta.

As such, the variant you’ve been exposed to, which you don’t normally know about, will also affect your chances of getting infected even if you’re vaccinated.(Credit: Meuhedet)(Credit: Meuhedet)


4 – Your immune system

All the data mentioned in this article and in the studies it cites refer to the average risk relative to the general population. It is important to remember that each of us is an individual case, and the risk of each person becoming infected is the result of a complicated equation consisting of the type of vaccine received, how many doses were taken and when, and the chances of one. person. of contracting the virus depending on your lifestyle. For example, medical workers or teachers often find themselves in situations where their chances of contracting the virus are higher.

But the strength of an individual’s immune system also plays a role.

The strength of the immune system generally decreases with age. Also, chronic or long-term medical conditions can weaken the immune response. That is why the elderly and the immunosuppressed tend to develop fewer antibodies after being vaccinated and are considered more vulnerable to infection.

In most countries, these groups have been given priority in vaccination, which means that they have been vaccinated in the early stages to protect them. But it also means that your immune defenses start to wane earlier.



Reference-www.jpost.com

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